First scale-up batch of DDD01510706 requested

Thanks to WCAIR’s scale-up infrastructure, we are able to make small amounts of tool compound available to collaborators for either in vitro or in vivo experimentation. Click HERE to find more information on how to request these items.

Since publishing our paper reporting use of KRSR and DDD01510706 as a second selection marker for genetic modification of Cryptosporidium, we have had requests for plasmid and compound from institutes in the following countries:

  • USA
  • UK
  • Australia
  • China

We were also able to scale-up a 2 gram batch and offer it for sale at cost to a research colleague. Compared to commercial sources, this is a greatly discounted price. We’re proud to be able to make our tool compounds, initially designed and synthesised by the DDU and scaled up by WCAIR, available to our fellow Cryptosporidium researchers both at small and larger scales.

Thanks to Beatriz Bargana for guidance, Gary Tarver for coordinating scale-up (including team member Gavin Wood), and James Hastie of the MRC PPU Reagents and Services.